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Elopag 50mg (Eltrombopag)

Product Name : Elopag 50
Generic Name : Eltrombopag
Formulation : Tablet
Available Pack Size : 14’s & 28’s
Available Strengths : 50 mg
Registrations : Bangladesh

Product Description

Eltrombopag is an orally bioavailable, small-molecule TPO-receptor agonist that interacts with the transmembrane domain of the human TPO-receptor. Eltrombopag is a stimulator of STAT and JAK phosphorylation. Unlike recombinant TPO or romiplostim, Eltrombopag does not activate the AKT pathway in any way. It should be noted that when given to patients with aplastic anemia, other lineages besides platelet count were increased, suggesting that either eltrombopag enhanced the effect of TPO in vivo; or there is a yet uncovered mechanism of action at work.