Ponaxen 15mg & 45mg (Ponatinib): Complete Guide, Uses, Dosage & Best Price
Ponaxen 15mg & 45mg (Ponatinib) is a clinically proven tyrosine kinase inhibitor (TKI) used in the treatment of resistant or intolerant forms of leukemia, especially Chronic Myeloid Leukemia (CML) and Philadelphia chromosome–positive Acute Lymphoblastic Leukemia (Ph+ ALL).
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What Is Ponaxen 15Mg & 45Mg (Ponatinib)?
Ponaxen Tablet 15mg & 45mg contains Ponatinib, a third-generation TKI designed to block mutated BCR-ABL proteins, including the highly resistant T315I mutation—a major cause of treatment failure in CML.
Key Attributes
- Highly effective in resistant CML
- Works even when first- or second-generation TKIs fail
- Targeted therapy with strong clinical outcomes
Medical Uses Of Ponaxen 15Mg & 45Mg
Ponaxen 15mg & 45mg is prescribed for:
Chronic Myeloid Leukemia (CML)
- Resistant CML
- Chronic phase, accelerated phase, or blast phase
Philadelphia Chromosome | Positive ALL (Ph+ ALL)
- Patients who do not respond to other TKIs
- Refractory or relapsed cases
T315I Mutation-Positive Leukemia
- Most critical indication
- Ponatinib is one of the only effective TKIs for T315I mutation
How Ponaxen Works | Mechanism Of Action
Targeting BCR-ABL1 Protein
Ponaxen blocks abnormal proteins that cause uncontrolled cancer cell growth.
Multi-Kinase Inhibition
Works on:
- BCR-ABL
- FGFR
- PDGFR
- VEGFR
This multi-targeted effect helps reduce disease progression and relapse rates.
Ponaxen 15Mg & 45Mg (Ponatinib) | Specification
| Parameter | Details |
| Brand Name | Ponaxen |
| Strength | 15mg & 45mg |
| Generic Name | Ponatinib |
| Therapeutic Class | Tyrosine Kinase Inhibitor |
| Used For | CML, Ph+ ALL |
| Manufacturer | Reputable oncology manufacturer |
| Availability | Online pharmacy |
| Purchase | Buy Ponaxen 15mg & 45mg |
Recommended Dosage
Strictly follow your oncologist’s dosage instructions.
Common Dosage
- 45mg once daily (standard initial dose)
- Dose may be adjusted to 30mg or 15mg depending on patient tolerance and response
Side Effects & Safety Information
Common Side Effects
- Hypertension
- Fatigue
- Skin rash
- Abdominal discomfort
- Headache
Serious Warnings
- Risk of arterial thrombosis
- Liver toxicity
- Pancreatitis
Seek emergency medical help if severe symptoms occur.
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