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Ibrucent 140 mg (Ibrutinib)

Product Name : Ibrucent
Generic Name : Ibrutinib
Formulation : Capsule
Available Pack Size : 90’s
Available Strengths : 140 mg
Registrations : Bangladesh

Product Description

Ibrutinib is a small-molecule inhibitor of BTK. Ibrutinib forms a covalent bond with a cysteine residue in the BTK active site, leading to inhibition of BTK enzymatic activity. BTK is a signaling molecule of the B-cell antigen receptor (BCR) and cytokine receptor pathways. BTK’s role in signaling through the B-cell surface receptors results in activation of pathways necessary for B-cell trafficking, chemotaxis, and adhesion. Nonclinical studies show that ibrutinib inhibits malignant B-cell proliferation and survival in vivo as well as cell migration and substrate adhesion in vitro.