Alecinix 150 MG (Alectinib)

Product Name : Alecinix
Generic Name : Alectinib
Formulation : Capsule
Available Pack Size : 120’s
Available Strengths : 150 mg
Registrations : Bangladesh

Product Information

Alecinix (Alectinib) 150mg is a highly selective, second-generation ALK (anaplastic lymphoma kinase) inhibitor used to treat ALK-positive non-small cell lung cancer (NSCLC) in adult patients, both as first-line or later-line treatment for metastatic disease and as adjuvant therapy after surgical resection. It works by blocking abnormal ALK signalling that drives tumour growth in this molecularly defined subset of lung cancer, and is notable for its activity against brain metastases. Manufactured for the Bangladesh market and globally supplied by Mediaid Pharmacy with worldwide shipping.

Basic Product Information of Alecinix (Alectinib) 150mg

Brand Name Alecinix (Alectinib)
Generic Name Alectinib INN (as Alectinib Hydrochloride)
Drug Class ALK (Anaplastic Lymphoma Kinase) Inhibitor
Available Strengths 150mg
Formulation Capsule
Pack Size 120 Capsules per Pack. At the standard dose of eight 150mg capsules daily, one pack provides a 15-day supply.
Primary Indication ALK-Positive Metastatic NSCLC, Adjuvant ALK-Positive NSCLC After Resection
Regulatory Approvals USFDA Approved (ALK-positive metastatic NSCLC; adjuvant treatment after resection of ALK-positive NSCLC, tumours ≥4cm or node positive). EMA Approved (ALK-positive NSCLC).
Originator Brand Alecensa by Genentech/Roche
Manufacturer [Manufacturer name to be confirmed], Bangladesh
Global Supplier Mediaid Pharmacy, Worldwide Shipping Available
Registration Registered in Bangladesh
Storage Conditions Store below 30 degrees Celsius. Keep in a dry place away from light and moisture. Keep out of the reach of children.

How Alecinix (Alectinib) Works

Alecinix contains Alectinib, a highly selective inhibitor of ALK (anaplastic lymphoma kinase). In a subset of NSCLC, a chromosomal rearrangement fuses the ALK gene with another gene (most commonly EML4), producing an abnormal EML4-ALK fusion protein that continuously signals cancer cells to grow and divide.

Alectinib works by binding to and blocking the ALK enzyme, interrupting this abnormal signalling and slowing or stopping tumour growth. As a second-generation ALK inhibitor, Alectinib is designed to achieve good penetration into the central nervous system, making it particularly effective at controlling and preventing brain metastases, a common and challenging complication of ALK-positive lung cancer.

Alecinix is taken as a twice-daily oral capsule with food, which is required for adequate absorption of the medication.

Indications for Alecinix (Alectinib)

Alecinix (Alectinib) is indicated for the following conditions, in patients with ALK-positive disease confirmed by an approved test:

ALK-Positive Metastatic NSCLC

For adult patients with metastatic NSCLC that is ALK-positive, as first-line treatment or following prior ALK-targeted therapy.

Adjuvant Treatment After Resection

For adult patients following surgical resection of ALK-positive NSCLC (tumours 4cm or larger, or with lymph node involvement), to reduce the risk of recurrence.

Benefits of Alecinix (Alectinib) 150mg

Strong CNS Activity

Well-documented activity against brain metastases, an important advantage given how frequently ALK-positive lung cancer spreads to the brain.

Preferred First-Line Option

Recommended in major treatment guidelines as a first-line option for ALK-positive advanced NSCLC, with strong progression-free survival data versus earlier ALK inhibitors.

Adjuvant Recurrence Reduction

Approved to help reduce the risk of recurrence after surgery in appropriately selected ALK-positive NSCLC patients.

No Clinically Relevant QT Effect

Clinical data have not shown clinically relevant QT interval prolongation with Alectinib, a distinguishing feature compared with some other kinase inhibitors.

Affordable Alternative to Alecensa

Alecinix contains the same active ingredient as Alecensa by Genentech/Roche, at a significantly lower cost.

WHO-GMP and cGMP Certified

Manufactured under strict WHO-GMP, cGMP, and ISO-certified standards, ensuring every batch of Alecinix meets consistent quality, safety, and efficacy requirements.

How to Take Alecinix (Alectinib)

Route: Oral, taken by mouth

Standard dose: 600mg (four 150mg capsules) taken twice daily, for a total of eight capsules (1200mg) per day.

With food: Must be taken with food, to ensure adequate absorption. Do not take on an empty stomach.

Swallowing: Swallow capsules whole. Do not open, dissolve, or chew the capsules.

Metastatic NSCLC treatment duration: Continued until disease progression or unacceptable toxicity, as determined by the treating oncologist.

Adjuvant treatment duration: Typically given for a total of 2 years, or until disease recurrence or unacceptable toxicity, whichever comes first.

Dose reduction for toxicity: If a dose reduction is needed, the typical steps are from 600mg twice daily to 450mg twice daily, and if further reduction is required, to 300mg twice daily, as directed by the treating physician.

Missed or vomited dose: If a dose is missed, it can be taken unless it is within 6 hours of the next scheduled dose, in which case skip it. If vomiting occurs, do not take an extra dose; wait for the next scheduled dose.

Prescription Medication. Alecinix should only be initiated and monitored by an oncologist or specialist physician, and only after confirmed ALK-positive status by an approved test. Regular liver function tests, heart rate monitoring, and CPK (muscle enzyme) checks are required, particularly during the first months of treatment. Always follow your prescribing physician’s exact instructions.

Monitoring and Dosage Adjustments

Regular monitoring is essential during Alecinix treatment. Your healthcare provider will monitor liver function tests every 2 weeks for the first 3 months, then periodically thereafter, given the risk of hepatotoxicity. Monitoring also includes heart rate and blood pressure for bradycardia, renal function, creatine phosphokinase (CPK) for muscle-related side effects, and complete blood counts for signs of haemolytic anaemia. Watchfulness for respiratory symptoms that could indicate interstitial lung disease is also important. Report any new muscle pain or weakness, unusual fatigue, dizziness, shortness of breath, or yellowing of the skin or eyes to your doctor promptly.

Drug Interactions and Important Information

Alectinib and its major active metabolite are metabolised primarily through CYP3A4. Avoid strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, and St. John’s Wort, as these can significantly reduce Alectinib levels and efficacy. Caution is advised with strong CYP3A4 inhibitors, and grapefruit or grapefruit juice should generally be avoided.

Alecinix can cause photosensitivity; patients should use sun protection and avoid prolonged sun exposure during treatment. Always inform your physician of all medications, supplements, and herbal products you are currently taking before starting Alecinix.

Side Effects and Precautions

Common Side Effects

Constipation

Oedema (swelling)

Myalgia (muscle pain)

Anaemia

Rash and photosensitivity

Fatigue

Nausea and vomiting

Elevated liver enzymes and bilirubin

Serious Warnings and Precautions

Hepatotoxicity, including drug-induced liver injury.

Interstitial lung disease / pneumonitis.

Severe myalgia with significant CPK elevation.

Bradycardia. Monitor heart rate, especially with other heart-rate-lowering medications.

Severe renal impairment.

Haemolytic anaemia.

Not recommended during pregnancy; embryo-fetal toxicity.

Who Should Use Alecinix (Alectinib)?

Alecinix is suitable for adult patients with ALK-positive metastatic NSCLC, confirmed by an approved diagnostic test, as first-line or subsequent treatment, and for adult patients receiving adjuvant treatment after surgical resection of ALK-positive NSCLC meeting the approved tumour size or nodal criteria. It is prescribed by oncologists and specialist physicians experienced in managing biomarker-driven lung cancer. Confirmed ALK testing, baseline liver function, heart rate assessment, and CPK levels are recommended before starting treatment.

Manufacturer

Alecinix (Alectinib) is manufactured in Bangladesh under strict WHO-GMP, cGMP, and ISO-certified standards, offering an affordable and bioequivalent alternative to Alecensa by Genentech/Roche at a fraction of the cost. [Please confirm the exact manufacturer name so it can be added here and in the specs table above.]

Global Supplier: Mediaid Pharmacy with Worldwide Shipping

Mediaid Pharmacy is a trusted global supplier of specialty oncology medications. We ensure Alecinix (Alectinib) is accessible to patients and healthcare providers worldwide through reliable worldwide shipping. Whether you are located in South Asia, the Middle East, Africa, Europe, or beyond, Mediaid Pharmacy provides fast and reliable delivery with full order support. Contact us directly via WhatsApp, phone, or WeChat for pricing, availability, and delivery enquiries.

Why Choose Alecinix (Alectinib) from Mediaid Pharmacy?

Alecinix represents a preferred targeted therapy option for patients with ALK-positive lung cancer, including those at risk of brain metastases. As the generic equivalent of Alecensa by Genentech/Roche, it delivers the same active ingredient, Alectinib, with the same proven ALK inhibition mechanism at a dramatically more affordable price. Manufactured under WHO-GMP and cGMP standards and distributed globally by Mediaid Pharmacy, Alecinix gives patients worldwide access to high-quality targeted lung cancer therapy without the financial burden of brand-name alternatives. For patients and physicians seeking a proven, affordable, and accessible Alectinib option with worldwide delivery, Alecinix from Mediaid Pharmacy is the trusted choice.

Frequently Asked Questions About Alecinix (Alectinib)

What is Alecinix (Alectinib) used for?

Alecinix (Alectinib) is a targeted ALK inhibitor used to treat ALK-positive non-small cell lung cancer (NSCLC), both in the metastatic setting as first-line or later-line treatment, and as adjuvant therapy after surgery for early-stage ALK-positive NSCLC. It works by blocking the abnormal ALK fusion protein that drives this type of lung cancer, and is particularly effective at controlling brain metastases.

How should I take Alecinix (Alectinib)?

Alecinix is taken as four 150mg capsules (600mg) twice daily, for eight capsules a day in total, and must always be taken with food for proper absorption. Always follow your prescribing physician’s exact instructions and do not stop or change your dose without medical advice.

What strength and pack size is Alecinix available in?

Alecinix is available as a 150mg capsule, supplied in packs of 120 capsules. Since the standard dose is eight capsules per day, one pack provides a 15-day supply.

Is Alecinix the same as Alecensa (Alectinib by Genentech/Roche)?

Yes. Alecinix is the generic equivalent of Alecensa. Both contain the same active ingredient, Alectinib, in the same dosage form and strength. Alecinix delivers the same clinical benefits as Alecensa at a significantly lower cost, making it a more accessible option for patients worldwide.

What are the side effects of Alecinix (Alectinib)?

Common side effects include constipation, swelling, muscle pain, anaemia, rash, and fatigue. Serious but less common risks include liver injury, lung inflammation, severe muscle toxicity, and slow heart rate. Regular monitoring of liver function, heart rate, and muscle enzymes is required throughout treatment. Always consult your physician for a complete assessment of your individual risks and benefits.

How long is Alecinix taken for?

For metastatic ALK-positive NSCLC, Alecinix is continued until the disease progresses or side effects become unacceptable. For adjuvant use after surgery, it is typically given for a total of 2 years, or until recurrence or unacceptable toxicity, whichever happens first. Your oncologist will confirm the exact duration for your situation.

Can I order Alecinix (Alectinib) online with worldwide shipping?

Yes. Mediaid Pharmacy supplies Alecinix (Alectinib) 150mg globally with worldwide shipping. Contact us via WhatsApp, phone, or WeChat at +8801773428128 or email us at info@mediaidpharmacy.com to enquire about pricing, availability, and delivery to your country.

Order Alecinix (Alectinib) 150mg with Worldwide Shipping

Phone / WhatsApp / WeChat: +8801773428128 | Email: info@mediaidpharmacy.com

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