Buy Dasanix 40 MG (Dasatinib) - Mediaid pharmacy

Dasanix 40 MG (Dasatinib)

Product Name : Dasanix
Generic Name : Dasatinib
Formulation : Tablet
Available Pack Size : 30’s (3×10’s)
Available Strengths : 40 mg
Registrations : Bangladesh

Message Us on WhatsApp

Product Information

Dasanix (Dasatinib) 40mg is a BCR-ABL tyrosine kinase inhibitor used to treat Philadelphia chromosome-positive Chronic Myeloid Leukaemia (Ph+ CML) and Philadelphia chromosome-positive Acute Lymphoblastic Leukaemia (Ph+ ALL) in adult and eligible paediatric patients. It works by blocking the abnormal BCR-ABL fusion protein that drives uncontrolled white blood cell production in these leukaemias. Manufactured for the Bangladesh market and globally supplied by Mediaid Pharmacy with worldwide shipping.

Basic Product Information of Dasanix (Dasatinib) 40mg

Brand Name	Dasanix (Dasatinib)
Generic Name	Dasatinib INN
Drug Class	BCR-ABL Tyrosine Kinase Inhibitor
Available Strengths	40mg
Formulation	Film-Coated Tablet
Pack Size	30’s (3 strips of 10 tablets). The number of 40mg tablets needed per day depends on the total dose prescribed by the physician.
Primary Indication	Philadelphia Chromosome-Positive CML (All Phases), Philadelphia Chromosome-Positive ALL
Regulatory Approvals	USFDA Approved (newly diagnosed chronic phase CML; chronic, accelerated, or blast phase CML resistant/intolerant to prior therapy including imatinib; Ph+ ALL; paediatric CML and ALL). EMA Approved (CML, Ph+ ALL).
Originator Brand	Sprycel by Bristol Myers Squibb
Manufacturer	[Manufacturer name to be confirmed], Bangladesh
Global Supplier	Mediaid Pharmacy, Worldwide Shipping Available
Registration	Registered in Bangladesh
Storage Conditions	Store below 30 degrees Celsius. Keep in a dry place away from light and moisture. Keep out of the reach of children.

How Dasanix (Dasatinib) Works

Dasanix contains Dasatinib, a kinase inhibitor that primarily targets the BCR-ABL fusion protein. In Philadelphia chromosome-positive leukaemias, a chromosomal translocation creates the abnormal BCR-ABL gene, producing a constantly “switched-on” tyrosine kinase enzyme that drives uncontrolled proliferation of white blood cells.

Dasatinib works by binding to and inhibiting BCR-ABL, as well as several related kinases including SRC-family kinases, c-KIT, and PDGFR, blocking the downstream signalling that leukaemic cells depend on for survival and division. Dasatinib is active against many BCR-ABL mutations that can develop resistance to earlier tyrosine kinase inhibitors such as imatinib, making it an important option for patients who have become resistant or intolerant to first-line therapy.

Dasanix is a once-daily oral tablet, taken with or without food, offering a convenient targeted therapy for long-term disease control in CML and Ph+ ALL.

Indications for Dasanix (Dasatinib)

Dasanix (Dasatinib) is indicated for the following conditions:

Newly Diagnosed Chronic Phase CML

For adult patients with newly diagnosed Philadelphia chromosome-positive CML in chronic phase.

CML Resistant or Intolerant to Prior Therapy

For adult patients with chronic, accelerated, or myeloid or lymphoid blast phase Ph+ CML with resistance or intolerance to prior therapy, including imatinib.

Philadelphia Chromosome-Positive ALL

For adult patients with Ph+ acute lymphoblastic leukaemia with resistance or intolerance to prior therapy.

Paediatric CML and Ph+ ALL

For eligible paediatric patients with Ph+ chronic phase CML or Ph+ ALL, using weight-based dosing.

Benefits of Dasanix (Dasatinib) 40mg

Effective in Imatinib-Resistant Disease

Active against many BCR-ABL mutations associated with resistance to first-generation tyrosine kinase inhibitors such as imatinib.

Established First-Line and Second-Line Option

Approved for both newly diagnosed chronic phase CML and for use after failure of prior therapy, across all phases of CML and in Ph+ ALL.

Simple Once-Daily Dosing

Taken once daily with or without food, replacing the earlier twice-daily regimen with a more convenient dosing schedule.

Affordable Alternative to Sprycel

Dasanix contains the same active ingredient as Sprycel by Bristol Myers Squibb, at a significantly lower cost, improving access to CML/ALL targeted therapy.

Paediatric Option Available

Approved for use in eligible children with Ph+ CML or Ph+ ALL using weight-based dosing.

WHO-GMP and cGMP Certified

Manufactured under strict WHO-GMP, cGMP, and ISO-certified standards, ensuring every batch of Dasanix meets consistent quality, safety, and efficacy requirements.

How to Take Dasanix (Dasatinib)

Route: Oral, taken by mouth

Standard dose, chronic phase CML: 100mg total once daily.

Standard dose, accelerated/blast phase CML or Ph+ ALL: 140mg total once daily.

Tablet count: Since Dasanix is supplied as a 40mg tablet, the number of tablets needed to reach the prescribed total daily dose will be specified by the prescribing physician and may differ from patient to patient, including for dose-reduced regimens.

With food: Can be taken with or without food, at about the same time each day.

Swallowing: Swallow tablets whole. Do not crush, cut, or chew the tablets.

Acid-reducing medications: Dasatinib solubility depends on stomach acidity. Avoid proton pump inhibitors. If an antacid is needed, it should be taken several hours before or after Dasanix; if an H2-receptor blocker is needed, separate its dosing from Dasanix as advised by your physician.

Paediatric dosing: Based on body weight, as determined by the treating haematologist/oncologist.

Missed dose: If a dose is missed, take the next scheduled dose at its normal time. Do not take an extra dose to make up for a missed one.

Prescription Medication. Dasanix should only be initiated and monitored by a haematologist, oncologist, or specialist physician experienced in managing CML or ALL. Complete blood counts must be checked regularly, and patients should be evaluated promptly for any new or worsening shortness of breath, cough, or chest discomfort, which can indicate fluid retention around the lungs. Always follow your prescribing physician’s exact instructions.

Monitoring and Dosage Adjustments

Regular monitoring is essential during Dasanix treatment. Your healthcare provider will monitor complete blood counts for thrombocytopenia, neutropenia, and anaemia, and watch closely for symptoms of fluid retention, such as new or worsening breathlessness, dry cough, or swelling, which may indicate pleural effusion and can require chest X-ray, dose interruption, diuretics, or a short course of steroids. Monitoring also includes cardiac assessment, given reported effects on heart function and QT interval, and watchfulness for symptoms of pulmonary arterial hypertension, such as progressive breathlessness or fatigue. Report any unusual bleeding, bruising, breathlessness, or chest discomfort to your doctor immediately.

Drug Interactions and Important Information

Dasatinib is metabolised primarily by CYP3A4. Avoid concomitant use of strong CYP3A4 inhibitors such as ketoconazole, itraconazole, clarithromycin, and ritonavir, as these can significantly increase Dasatinib levels. Avoid strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, and St. John’s Wort, as these can reduce Dasatinib efficacy; if unavoidable, a dose increase may be considered by the prescribing physician.

Because Dasatinib solubility is pH-dependent, acid-reducing medications, particularly proton pump inhibitors, should be avoided, as they can substantially reduce absorption and efficacy. Use caution with medications that inhibit platelet function or with anticoagulants, as these may increase bleeding risk. Always inform your physician of all medications, supplements, and herbal products you are currently taking before starting Dasanix.

Side Effects and Precautions

Common Side Effects

Fluid retention (superficial oedema, pleural effusion)

Diarrhoea

Headache

Fatigue

Musculoskeletal pain

Rash

Nausea

Dyspnoea (shortness of breath)

Serious Warnings and Precautions

Severe myelosuppression: thrombocytopenia, neutropenia, and anaemia. Regular blood count monitoring is required.

Severe fluid retention, including pleural and pericardial effusion, pulmonary oedema, and ascites.

Bleeding events, including severe haemorrhage.

Cardiovascular toxicity, including cardiac dysfunction and QT interval prolongation.

Pulmonary arterial hypertension, which may be reversible on discontinuation.

Not recommended during pregnancy; embryo-fetal toxicity.

Who Should Use Dasanix (Dasatinib)?

Dasanix is suitable for adult patients with newly diagnosed or previously treated Philadelphia chromosome-positive CML, across chronic, accelerated, and blast phases, and adult patients with Ph+ ALL who have not responded adequately to or cannot tolerate prior therapy. Eligible paediatric patients with Ph+ CML or Ph+ ALL may also be treated using weight-based dosing. It is prescribed by haematologists and oncologists experienced in managing leukaemia. Baseline blood counts and cardiopulmonary assessment are recommended before starting treatment.

Manufacturer

Dasanix (Dasatinib) is manufactured in Bangladesh under strict WHO-GMP, cGMP, and ISO-certified standards, offering an affordable and bioequivalent alternative to Sprycel by Bristol Myers Squibb at a fraction of the cost. [Please confirm the exact manufacturer name so it can be added here and in the specs table above.]

Global Supplier: Mediaid Pharmacy with Worldwide Shipping

Mediaid Pharmacy is a trusted global supplier of specialty oncology and haematology medications. We ensure Dasanix (Dasatinib) is accessible to patients and healthcare providers worldwide through reliable worldwide shipping. Whether you are located in South Asia, the Middle East, Africa, Europe, or beyond, Mediaid Pharmacy provides fast and reliable delivery with full order support. Contact us directly via WhatsApp, phone, or WeChat for pricing, availability, and delivery enquiries.

Why Choose Dasanix (Dasatinib) from Mediaid Pharmacy?

Dasanix represents an important targeted therapy option for patients with Ph+ CML and Ph+ ALL. As the generic equivalent of Sprycel by Bristol Myers Squibb, it delivers the same active ingredient, Dasatinib, with the same proven BCR-ABL inhibition mechanism at a dramatically more affordable price. Manufactured under WHO-GMP and cGMP standards and distributed globally by Mediaid Pharmacy, Dasanix gives patients worldwide access to high-quality leukaemia therapy without the financial burden of brand-name alternatives. For patients and physicians seeking a proven, affordable, and accessible Dasatinib option with worldwide delivery, Dasanix from Mediaid Pharmacy is the trusted choice.

Frequently Asked Questions About Dasanix (Dasatinib)

What is Dasanix (Dasatinib) used for?

Dasanix (Dasatinib) is a BCR-ABL tyrosine kinase inhibitor used to treat Philadelphia chromosome-positive Chronic Myeloid Leukaemia (CML), across chronic, accelerated, and blast phases, and Philadelphia chromosome-positive Acute Lymphoblastic Leukaemia (Ph+ ALL) in adults and eligible children. It works by blocking the abnormal BCR-ABL protein that drives these leukaemias.

How should I take Dasanix (Dasatinib)?

Dasanix is taken orally once daily, with or without food. The standard total dose is 100mg once daily for chronic phase CML, or 140mg once daily for accelerated/blast phase CML or Ph+ ALL; your physician will specify how many 40mg tablets this requires. Always follow your prescribing physician’s exact instructions and avoid proton pump inhibitors unless otherwise advised.

What strength and pack size is Dasanix available in?

Dasanix is available as a 40mg tablet, supplied as 30’s (3 strips of 10 tablets). Since standard total doses are 100mg or 140mg once daily, most patients will need more than one 40mg tablet per day; your physician will specify the exact number.

Is Dasanix the same as Sprycel (Dasatinib by Bristol Myers Squibb)?

Yes. Dasanix is the generic equivalent of Sprycel. Both contain the same active ingredient, Dasatinib, in the same dosage form. Dasanix delivers the same clinical benefits as Sprycel at a significantly lower cost, making it a more accessible option for patients worldwide.

What are the side effects of Dasanix (Dasatinib)?

Common side effects include fluid retention (swelling or pleural effusion), diarrhoea, headache, fatigue, and rash. Serious but less common risks include severe myelosuppression, significant fluid retention around the lungs or heart, bleeding, cardiovascular effects, and pulmonary arterial hypertension. Always consult your physician for a complete assessment of your individual risks and benefits before starting treatment.

Can Dasanix be taken with antacids or acid-reducing medications?

Proton pump inhibitors should be avoided, as they can significantly reduce Dasatinib absorption. If an antacid or H2-receptor blocker is needed, it should be timed several hours apart from your Dasanix dose, as advised by your physician. Always review your complete medication list with your prescribing physician before starting Dasanix.

Can I order Dasanix (Dasatinib) online with worldwide shipping?

Yes. Mediaid Pharmacy supplies Dasanix (Dasatinib) 40mg globally with worldwide shipping. Contact us via WhatsApp, phone, or WeChat at +8801773428128 or email us at info@mediaidpharmacy.com to enquire about pricing, availability, and delivery to your country.

Order Dasanix (Dasatinib) 40mg with Worldwide Shipping

Phone / WhatsApp / WeChat: +8801773428128 | Email: info@mediaidpharmacy.com

Message on WhatsApp