Specialty medicines • Bangladesh

LuciSeta 200 MG & 400 MG (Sparsentan)

LuciSeta — Sparsentan. Manufactured by Lucius Pharmaceuticals (Lao) Co., Ltd.

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Description

Sparsentan

Each film-coated tablet contains: Sparsentan … 400mg

INDICATION

LuciSeta is an endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression, generally a urine protein-tocreatinine ratio (UPCR) ≥1.5 g/g.

DOSAGE AND USE

Prior to initiating treatment with LuciSeta, discontinue use of renin-angiotensinaldosterone system (RAAS) inhibitors, endothelin receptor antagonists (ERAs) or aliskiren. Initiate treatment with LuciSeta at 200 mg orally once daily. After 14 days, increase the recommended dose of 400 mg once daily, as tolerated. When resuming treatment with LuciSeta after an interruption, consider titration of LuciSeta, starting at 200 mg once daily. After 14 days, increase to the recommended dose of 400 mg once daily. Tablet should be swallowed whole & not chewed or crushed.

STORAGE

In a dry place and store at 20°C to 25°C.

MANUFACTURED AND MARKETED BY

LUCIUS PHARMACEUTICALS(LAO) CO., LTD No.26, Thongmang village, Xaythany district, Vientiane Capital, Laos

WARNING

Keep medicine out of reach of Children. Do not administered LuciSeta in Pregnancy and Lactation patient treatment.

Sparsentan

Each film-coated tablet contains: Sparsentan … 200mg.

INDICATION

LuciSeta is an endothelin and angiotensin II receptor antagonist indicated to reduce proteinuria in adults with primary immunoglobulin A nephropathy (IgAN) at risk of rapid disease progression, generally a urine protein-to-creatinine ratio (UPCR) ≥1.5 g/g.

DOSAGE AND USE

• Prior to initiating treatment with LuciSeta, discontinue use of renin -angiotensin- aldosterone system (RAAS) inhibitors, endothelin receptor antagonists (ERAs) or aliskiren. • Initiate treatment with LuciSeta at 200 mg orally once daily. After 14 days, increase to the recommended dose of 400 mg once daily, as tolerated. When resuming treatment with LuciSeta after an interruption, consider titration of LuciSeta, starting at 200 m g once daily. After 14 days, increase to the recommended dose of 400 mg once daily. Tablets should be swallowed whole & not chewed or crushed.

STORAGE

In a dry place and store at 20℃ to 25℃.

WARNING

Keep medicine out of reach of Children. Do not administer LuciSeta during Pregnancy and Lactation.

PLEASE SEE PACKAGE INSERT

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