Mezoxia 160 MG (Megestrol)

Product Name : Mezoxia
Generic Name : Megestrol
Formulation : Tablet
Available Pack Size : 30’s
Available Strengths : 160 mg
Registrations : Export Only

Product Information

Mezoxia (Megestrol Acetate) 160mg is a synthetic progestin used for the palliative treatment of advanced breast and endometrial carcinoma, and to manage anorexia, cachexia, or unexplained significant weight loss associated with cancer or AIDS. It works by suppressing pituitary gonadotropin (LH) and oestrogen release, alongside direct hormonal effects on tumour tissue, and separately stimulates appetite and promotes weight gain through mechanisms not yet fully understood. Manufactured by Everest Pharmaceuticals Ltd., Bangladesh and globally supplied by Mediaid Pharmacy with worldwide shipping.

Basic Product Information of Mezoxia (Megestrol Acetate) 160mg

Brand Name Mezoxia (Megestrol Acetate)
Generic Name Megestrol Acetate
Drug Class Synthetic Progestin (Progestogen)
Available Strength 160mg
Formulation Tablet
Pack Size 30 Tablets per Pack
Primary Indication Advanced Breast Carcinoma, Advanced Endometrial Carcinoma and Cancer/AIDS-Associated Anorexia-Cachexia
Regulatory Approvals USFDA Approved (Breast Carcinoma, Endometrial Carcinoma, AIDS-Related Anorexia/Cachexia).
Originator Brand Megace by Bristol Myers Squibb / Mead Johnson
Manufacturer Everest Pharmaceuticals Ltd., Dhaka, Bangladesh
Global Supplier Mediaid Pharmacy, Worldwide Shipping Available
Registration Status Export Only – Manufactured for International Markets
Storage Conditions Store below 30 degrees Celsius. Keep in a dry place away from light and moisture. Keep out of the reach of children.

How Mezoxia (Megestrol Acetate) Works

Mezoxia contains Megestrol Acetate, a synthetic derivative of the natural hormone progesterone. In hormone-sensitive breast and endometrial cancers, Megestrol is thought to act by suppressing luteinising hormone (LH) and oestrogen release from the anterior pituitary gland, alongside a direct, local antitumour effect within cancer tissue, though the precise mechanism has not been fully established.

Separately, Megestrol has a well-documented effect of stimulating appetite and promoting weight gain, an effect linked to an increase in both fat mass and body cell mass. This effect forms the basis for its use in patients experiencing anorexia, cachexia, or unexplained significant weight loss related to cancer or AIDS, helping to improve nutritional status and quality of life even when the underlying disease cannot be cured.

Mezoxia is taken as an oral tablet, with the dose and frequency tailored to the specific condition being treated, whether that is hormone-responsive cancer or appetite and weight support.

Indications for Mezoxia (Megestrol Acetate)

Mezoxia (Megestrol Acetate) is indicated for the following conditions:

Advanced Breast Carcinoma

For the adjunctive or palliative treatment of recurrent, inoperable, or metastatic breast carcinoma.

Advanced Endometrial Carcinoma

For the palliative treatment of recurrent, inoperable, or metastatic endometrial carcinoma.

Anorexia, Cachexia, or Unexplained Weight Loss

For male and female patients experiencing anorexia, cachexia, or unexplained significant weight loss associated with cancer or AIDS.

Benefits of Mezoxia (Megestrol Acetate) 160mg

Dual Role in Oncology Care

Mezoxia offers both a hormonal treatment option for advanced breast and endometrial cancer, and separately, meaningful appetite and weight support for patients with cancer-related cachexia.

Improves Nutritional Status

Clinical studies have shown Megestrol Acetate significantly improves appetite and supports weight gain in patients with cancer-associated wasting, helping maintain strength and quality of life.

Convenient Oral Tablet

Mezoxia is taken as an oral tablet rather than an injectable hormone therapy, making it straightforward to incorporate into a patient’s daily routine.

Affordable Alternative to Megace

Mezoxia contains the same active ingredient as Megace, at a significantly lower cost, making palliative hormone therapy and appetite support more financially accessible.

Flexible Dosing

The 160mg tablet strength allows straightforward dosing for breast cancer, and can be combined in multiples for the higher, individually titrated doses used in endometrial cancer or appetite stimulation.

cGMP Certified Manufacturing

Produced by Everest Pharmaceuticals Ltd. under cGMP-compliant manufacturing standards, helping ensure consistent quality, purity, and potency in every batch of Mezoxia tablets.

How to Take Mezoxia (Megestrol Acetate)

Route: Oral, taken by mouth, with or without food.

Standard dose for breast carcinoma: 160mg (one tablet) per day, either as a single daily dose or in divided doses, exactly as directed by the prescribing physician.

Standard dose for endometrial carcinoma: 40mg to 320mg per day, given in divided doses, individualised based on response and tolerability.

Dose for anorexia, cachexia, or unexplained weight loss: Doses generally range from 160mg to 800mg per day, with meaningful appetite and weight improvement seen even at the lower end of this range in some patients, and higher doses used where a greater or faster response is needed. Your physician will determine and titrate the appropriate dose for your situation.

Missed dose: If a dose is missed, take it as soon as remembered unless it is close to the next scheduled dose, in which case skip the missed dose; do not double up doses.

Stopping treatment: Do not stop Mezoxia abruptly after prolonged use without medical guidance, as this can be associated with symptoms of adrenal insufficiency; your physician may advise a gradual taper, particularly around times of physical stress, illness, or surgery.

Paediatric use: The safety and efficacy of Mezoxia in children have not been well established for most indications. Follow specialist paediatric guidance where relevant.

Prescription Medication. Mezoxia has been associated with thromboembolic events, including deep vein thrombosis and pulmonary embolism, some of which have been fatal. Long-term use may suppress adrenal (pituitary-adrenal) function, with symptoms of adrenal insufficiency reported on withdrawal, particularly during physical stress. Mezoxia can also cause or worsen hyperglycaemia. Mezoxia must only be prescribed and monitored by a physician experienced in managing hormone therapy and cancer-associated cachexia.

Monitoring and Dosage Adjustments

Regular monitoring is recommended throughout Mezoxia treatment. Your physician will monitor for signs of blood clots, such as leg swelling, pain, or sudden breathlessness, blood glucose levels, particularly in patients with diabetes or risk factors for it, and signs of fluid retention such as swelling or worsening heart failure symptoms. In patients on long-term therapy who face surgery, illness, or other physical stress, your physician will consider the possibility of adrenal suppression and may provide additional corticosteroid coverage if needed. Report any leg swelling or pain, sudden breathlessness, chest pain, unusual vaginal bleeding, or symptoms of high blood sugar (increased thirst, frequent urination) to your doctor promptly.

Drug Interactions and Important Information

Use with caution alongside other medications that affect blood clotting risk, and inform your physician of any personal or family history of thromboembolic disease before starting treatment. Megestrol Acetate is completely metabolised in the liver; inform your physician of any liver conditions or other medications that affect hepatic metabolism.

Inform your physician of any history of diabetes, blood clots, or adrenal or pituitary conditions before starting treatment. Mezoxia is not indicated for use in men or in women who are pregnant, as it may cause harm to a developing foetus; women of childbearing potential should discuss appropriate contraception with their physician. Always inform your physician of all medications, supplements, and herbal products you are currently taking before starting Mezoxia.

Side Effects and Precautions

Common Side Effects

Weight gain and increased appetite

Nausea and vomiting

Oedema (fluid retention)

Breakthrough vaginal bleeding or discharge

Hot flashes and mood changes

Asthenia (weakness) and rash

Diarrhoea and flatulence (particularly with cachexia use)

Serious Warnings and Precautions

Thromboembolic events, including deep vein thrombosis and pulmonary embolism, in some cases fatal.

Adrenal (pituitary-adrenal axis) suppression with long-term use, and adrenal insufficiency symptoms possible on withdrawal.

Hyperglycaemia, which may unmask or worsen diabetes.

Cushingoid features and fluid retention with long-term or high-dose use.

Tumour flare, sometimes with hypercalcaemia, early in breast cancer treatment.

Not recommended during pregnancy.

Who Should Use Mezoxia (Megestrol Acetate)?

Mezoxia is suitable for adult patients with recurrent, inoperable, or metastatic breast carcinoma or advanced endometrial carcinoma being managed with palliative hormone therapy, and for male or female patients experiencing anorexia, cachexia, or unexplained significant weight loss due to cancer or AIDS. It is prescribed by oncologists, palliative care physicians, and infectious disease specialists as appropriate to the underlying condition. A thorough medical assessment including a review of clotting risk, diabetes status, and adrenal function is recommended before initiating treatment.

Manufacturer: Everest Pharmaceuticals Ltd.

Everest Pharmaceuticals Ltd. is a vertically integrated pharmaceutical company based in Dhaka, Bangladesh, focused on complex, technology-driven specialty medicines across oncology, nephrology, and virology. Operating under Bangladesh’s TRIPS/Doha Declaration exemption for least-developed countries, Everest manufactures advanced generics such as Mezoxia under cGMP-compliant standards, with the stated mission of making high-cost, life-saving medicines accessible and affordable to patients around the world. Mezoxia offers a bioequivalent alternative to Megace at a fraction of the cost.

Global Supplier: Mediaid Pharmacy with Worldwide Shipping

Mediaid Pharmacy is a trusted global supplier of specialty and oncology medications. We ensure Mezoxia (Megestrol Acetate) is accessible to patients and healthcare providers worldwide through reliable worldwide shipping. Whether you are located in South Asia, the Middle East, Africa, Europe, or beyond, Mediaid Pharmacy provides fast and reliable delivery with full order support. Contact us directly via WhatsApp, phone, or WeChat for pricing, availability, and delivery enquiries.

Why Choose Mezoxia (Megestrol Acetate) from Mediaid Pharmacy?

Mezoxia represents a well-established option for both hormone-responsive cancer therapy and cancer-related appetite support. As the generic equivalent of Megace, it delivers the same active ingredient, Megestrol Acetate, with the same proven mechanism at a dramatically more affordable price. Manufactured by Everest Pharmaceuticals Ltd. under cGMP-compliant standards and distributed globally by Mediaid Pharmacy, Mezoxia gives patients worldwide access to effective palliative and supportive care without the financial burden of brand-name alternatives. For patients and physicians seeking a proven, affordable, and accessible Megestrol Acetate option with worldwide delivery, Mezoxia from Mediaid Pharmacy is the trusted choice.

Frequently Asked Questions About Mezoxia (Megestrol Acetate)

What is Mezoxia (Megestrol Acetate) used for?

Mezoxia (Megestrol Acetate) is used for the palliative treatment of advanced or recurrent breast and endometrial cancer, and to treat anorexia, cachexia, or unexplained significant weight loss in patients with cancer or AIDS. It works partly through hormonal effects on tumour tissue and partly through a separate, well-documented appetite-stimulating effect.

How should I take Mezoxia (Megestrol Acetate)?

Mezoxia is taken orally, with or without food. The standard dose for breast cancer is 160mg per day. Endometrial cancer and appetite-stimulation dosing vary more widely and are individually titrated by your physician based on response. Always follow your physician’s exact instructions, and do not stop treatment abruptly after long-term use without medical guidance.

What strength is Mezoxia available in?

Mezoxia is available in a 160mg tablet, supplied in a pack of 30 tablets. Higher doses used for endometrial cancer or appetite stimulation are achieved by taking multiple tablets or splitting the daily dose, exactly as prescribed by your physician.

Is Mezoxia the same as Megace (Megestrol Acetate)?

Yes. Mezoxia is the generic equivalent of Megace. Both contain the same active ingredient, Megestrol Acetate. Mezoxia is manufactured by Everest Pharmaceuticals Ltd. in Bangladesh and offers the same clinical mechanism as Megace at a significantly lower cost.

What are the side effects of Mezoxia (Megestrol Acetate)?

Common side effects include weight gain, nausea, fluid retention, and breakthrough bleeding. Serious but less common risks include blood clots, adrenal suppression with long-term use, and worsening of blood sugar control. Always consult your physician for a complete assessment of your individual risks and benefits before starting treatment.

Can Mezoxia be used with other medications?

Use caution combining Mezoxia with other medications that affect blood clotting risk, and inform your physician of any history of diabetes or adrenal or pituitary conditions. Always inform your physician of all medications, supplements, and herbal products you are taking before starting Mezoxia.

Is Mezoxia (Megestrol Acetate) safe during pregnancy or breastfeeding?

No. Mezoxia is not recommended during pregnancy, as it may cause harm to a developing foetus. Please consult your physician before starting treatment if you are pregnant, planning to become pregnant, or breastfeeding.

Can I order Mezoxia (Megestrol Acetate) online with worldwide shipping?

Yes. Mediaid Pharmacy supplies Mezoxia (Megestrol Acetate) 160mg globally with worldwide shipping. Contact us via WhatsApp, phone, or WeChat at +8801773428128 or email us at info@mediaidpharmacy.com to enquire about pricing, availability, and delivery to your country.

Order Mezoxia (Megestrol Acetate) 160mg with Worldwide Shipping

Phone / WhatsApp / WeChat: +8801773428128 | Email: info@mediaidpharmacy.com

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